How to change upload_store path?

Hello,

i have a big server with many devices.
My php script is now looking for the disk, wich is empty.

How can i now change automaticly the upload_store path, without changing
the nginx config file and reaload nginx?
Can i do this?

My php script is like rotating the disks where to upload.

I hope you understand my problem,
best regards
Simon

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